James Milner handed record 654th Premier League appearance in Brighton's clash with Brentford.
Brentford make two changes from last league fixture as Aaron Hickey and Jordan Henderson both start.
Dominic Calvert-Lewin starts up front as Leeds change 9 from FA Cup win for trip to Aston Villa.
Ollie Watkins starts up front as one of seven Aston Villa changes for home clash with Leeds.
Burnley unchanged from last league game as Lesley Ugochukwu starts against former club Chelsea.
Wesley Fofana, Pedro Neto and Reece James all come into Chelsea team for visit of Burnley.
Constitution Hill won comfortably on his debut on the Flat at Southwell on Friday evening.