Declan Rice and Ben White return to England squad but Cole Palmer and Phil Foden are left out.
Josh King and Jobe Bellingham feature as Thomas Tuchel names his England squad to face Croatia.
Hearts beaten 3-1 at Thun in the Conference League to remain winless in the competition.
Brighton won 1-0 at Getafe in the Conference League, with Malick Yalcouye heading home the winner.
Regis Le Bris under pressure after Sunderland lost 2-0 at home to Dinamo Zagreb in Europa League.
Celtic came from two goals down to clinch a 3-2 Europa League victory at home to Besiktas.
Evanilson and Rayan netted late on as Bournemouth won 3-1 at Sparta Prague in the Europa League.